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Opiniones y comentarios de aprendices correspondientes a Basic Principles of Cell Signaling por parte de Instituto Avanzado de Ciencia y Tecnología de Corea (KAIST)

44 calificaciones

Acerca del Curso

The coordination of life in multicellular organisms is precisely controlled by cells via various internal and external signals. Cells depend on different types of signals to regulate their growth, division, metabolism as well as death. Signals are growth factors or hormones produced and secreted by other cells. Some signals such as nutrients are in the form of molecules from the environment. Signaling molecules are sensed by direct binding to specific receptor molecules. Depending on the biochemical properties and ways of molecules changes, we can group various signaling events in defined pathways. Throughout specific signal transduction pathways, a signal can modulate cellular activities and gene expression, thereby leading to changes in cell growth, metabolism, differentiation, or many other cellular functions. When genetic mutations or biochemical changes occur in key proteins of certain cellular signaling pathways, cellular homeostasis can be disrupted, thus triggering tissue malfunctions, itiation or spread of cancer, or developmental anomalies. Dissecting biochemical principles of these cell signaling pathways is essential for us to better understand mechanisms of both normal cells and pathological conditions, therefore our knowledge on signal transduction will provide valuable information to develop effective therapeutic agents to fight against diseases.. This 6 week-course will give you a solid introduction to the basic fundamentals of cell signaling. I will first define the concept of cell signaling and introduces major types of cellular signaling events. Throughout 6 weeks, we will study biochemical basis of electrical signaling, chemical signaling as well as gap junction-mediated signaling pathways. We will also learn about key principles underlying signal transduction pathways by studying significance of protein-protein interactions and signaling second messengers. In the end of each week, dysregulated cell signaling in pathological conditions such as cancer and diabetes will be presented and discussed. Everyone knows that cell signaling is essential for sustaining life. How can you explain insulin actions in lowering glucose in biochemical details? What can be the fundamental mode of oxygen sensing in our body? Have you ever thought about ways of how we can specifically remove or kill certain types of rapidly-growing cancer cells? Cell signaling accompanies various biochemical strategies to sense and transmit signals inside our cells. Without fine control of those signaling processes, cells, tissues, and organisms cannot maintain life....

Principales reseñas


1 de ago. de 2021

Excelente! Me pareció que el curso proveee conocimientos muy adecuados para quienes empiezan con el estudio de las cascadas de senalización celular.


16 de ago. de 2022

I am very thanful for all those who provide us this amzing learning plateform. I have learnt more than my expectations.

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1 - 15 de 15 revisiones para Basic Principles of Cell Signaling

por G D

10 de ene. de 2022

This is an excellent course on topics that are very important in biological and medical science. They are especially important in my field (clinical haematology and oncology). As just one example, many tyrosine kinase inhibitors effective against various malignancies have been developed. These agents inhibit pathways driving uncontrolled proliferation of the malignant cells. Knowledge of these pathways is essential for development of these and other new treatments for many diseases, not just cancer. I think that the professor presented the material in about as clear and concise a manner as is possible. I should note that my background in medicine and research in biochemistry made the material very comprehensible to me, and I knew quite a bit of it already. Nevertheless, I think that anyone with even minimal knowledge or interest in biology, biochemistry, medicine, etc., would benefit from this course, especially in view of the importance of the topics.

por WEE F C

27 de abr. de 2022

This is a very interesting course, and useful in understanding the cell signaling pathways. This is very useful for understanding the development of cancer cells, their metastasis using cells signals. It is also useful to understand and try to explain some of the cells signals that maybe affected by messengers cells. The professor who taught this explains well with his diagrams and teaching.

por Parnia k

4 de abr. de 2022

I benefited hugely by this course. It was an informatic course about major signaling pathways. It did not go into all the details of each signaling pathway but provided basic and important information. so, It is so suitable for people with no background. The only problem was the english subtitle, some words were mistransleted and It could be confusing.

por preyanka n

5 de may. de 2022

this is a fantastic course. I learned a lot. But since we can not download any slide, this is a disadvantage since there are a lot of images essential to understand the signaling. So i would like to request to avail the option of dowloading the slides.

por Juan F C

18 de jul. de 2021

Great course, simply awesome! All the topics are very interesting, the lectures include graphs and images illustrating the molecular pathways which makes them engaging. Professor Kim is great.

por Juan C R N

2 de ago. de 2021

Excelente! Me pareció que el curso proveee conocimientos muy adecuados para quienes empiezan con el estudio de las cascadas de senalización celular.

por adriana z

18 de jul. de 2021

The course is complete. Extremely didactic and objective.Great for those who want to get started in the field, or even learn the main concepts.

por Israr U D

17 de ago. de 2022

I am very thanful for all those who provide us this amzing learning plateform. I have learnt more than my expectations.

por Suraj

19 de may. de 2022

the course provided a very useul and a huge amount of knowledge! grateful for the this opportunity to take this course!

por Rakesh A P

1 de jun. de 2022

The course was informative and helped me grow my skills and helped me develop my knowledge base.

por C T

14 de abr. de 2022

An exceptional course with remarkable slides. It is very understandable.


17 de jul. de 2021

This course is extremely helpful to understand cell signaling.

por mahmoud h

28 de ago. de 2022

I really loved it


22 de mar. de 2022

Amazing course

por Vickie R R

5 de ago. de 2022

I enjoyed the class as it added to my knowledge and was organized nicely.

However, the transcripts were riddled with mistakes, worse than I've seen with any coursera course. I had some familiarity with the topic and was able to correct the translation from spoken to written but a better system needs to be installed when using a lot of very specific scientific terminology. What ever system you were using, it didn't work. I realize this course came from Korea and perhaps English was not the professor's first language but it was quite laughable to see the riducules mistakes made for words such as kinase (kindness( and binding (combined) when the professor was saying the correct term.

In addition, the quiz and exam questions were poorly written with a number of grammar mistakes making it difficult to interpret the questions.